Biography

Dr Shane Nanayakkara is an Interventional Cardiologist with a special interest in structural heart interventions and heart failure. He currently consults at The Alfred, Cabrini Health, Epworth Health, and is in private practice at Heart Clinic Melbourne and Bayside Heart.

Dr Nanayakkara completed his Bachelor of Medicine, Bachelor of Surgery at Monash University and went on to specialise in cardiology. He completed training at a number Read More...

Procedures & Conditions

Procedures Performed
  • Balloon Aortic Valvuloplasty
  • Cardiac Catheterisation
  • Coronary Angiography
  • Coronary Stenting
  • Echocardiography
  • Fractional Flow Reserve and Pressure Wire
  • General Cardiology
  • Intravascular Ultrasound Imaging
  • Invasive Cardiology
  • MitraClip Transcatheter Mitral Valve Repair Device
  • Mechanical Support Devices (Impella CP)
  • Patent Foramen Ovale (PFO) Closures
  • Percutaneous Aortic Valve Procedures
  • Percutaneous Coronary Intervention (PCI)
  • Percutaneous Mitral Valve Procedures
  • Percutaneous Structural Heart Intervention
  • Pressure Wire Assessment of Coronary Artery Disease
  • Right Heart Catheterisation
  • Rotablator
  • Transcatheter Aortic Valve Implantation (TAVI)
  • Transcatheter Mitral Valve Implantation
  • Transfemoral and Alternate Access TAVI
  • Valve in Valve TAVI Procedures
Conditions Treated
  • Acute Coronary Syndrome
  • Aortic Stenosis
  • Aortic Valve Disease
  • Cardiac Disease
  • Cardiomyopathy
  • Chronic Heart Failure
  • Coronary Artery Disease
  • Dilated Cardiomyopathy
  • Dyspnoea
  • General Cardiology
  • Heart Failure
  • Structural Heart Disease
  • Ischemic Cardiomyopathy
  • Mitral Regurgitation
  • Mitral Valve Disease
  • Palpitations
  • Preventative Cardiology
  • Structural Heart Disease
  • Valvular Heart Disease

Experience

  • Consultant Interventional Cardiologist
    The Alfred 2016 - Present
  • Consultant Interventional Cardiologist
    Cabrini Malvern 2020 - Present
  • Consultant Interventional Cardiologist
    Epworth Health 2020 - Present
  • Consultant Cardiologist
    Heart Clinic Melbourne 2020 - Present
  • Consultant Cardiologist
    Bayside Heart 2020 - Present
  • Research Fellow
    Baker IDI Heart and Diabetes Institute 2016 - Present
  • Teaching Associate
    Monash University 2016 - Present
  • PhD Scholar
    Monash University 2016 - 2019

Memberships

Professional Memberships and Affiliations
  • 2015

    Fellow of the Royal Australasian College of Physicians (Cardiology)

  • Member of the Cardiac Society of Australia and New Zealand (CSANZ)

Awards
  • National Heart Failure Prize from the Cardiac Society of Australia and New Zealand

  • Mollie Holman medal for best thesis from Monash University

Research & Publications

Publications

1. (2021). Comprehensive Physiological Modeling Provides Novel Insights Into Heart Failure With Preserved Ejection Fraction Physiology. Journal of the American Heart Association. 10.1161/JAHA.121.021584.

2. Haregu, Tilahun N & Nanayakkara, Shane & Carrington, Melinda & Kaye, David. (2021). Multimorbidity and multiple causes of death in heart failure. Journal of Public Health. 29. 10.1007/s10389-020-01223-0.

3. Beale, Anna & O’Donnell, Joanne & Nakai, Michael & Nanayakkara, Shane & Vizi, Donna & Carter, Kaye & Dean, Eliza & Ribeiro, Rosilene & Yiallourou, Stephanie & Carrington, Melinda & Marques, Francine & Kaye, David. (2021). The Gut Microbiome of Heart Failure With Preserved Ejection Fraction. Journal of the American Heart Association. 10. e020654. 10.1161/JAHA.120.020654.

4. Beale, Anna & O’Donnell, Joanne & Nakai, Michael & Nanayakkara, Shane & Vizi, Donna & Carter, Kaye & Dean, Eliza & Ribiero, Rosilene & Yiallourou, Stephanie & Carrington, Melissa & Marques, Francine & Kaye, David. (2021). THE MICROBIOME OF HEART FAILURE WITH PRESERVED EJECTION FRACTION. Journal of the American College of Cardiology. 77. 721. 10.1016/S0735-1097(21)02080-5.

5. Sugumar, Hariharan & Nanayakkara, Shane & Vizi, Donna & Wright, Leah & Chieng, David & Leet, Angeline & Mariani, Justin & Voskoboinik, Alex & Prabhu, Sandeep & Taylor, Andrew & Kalman, Jonathan & Kistler, Peter & Kaye, David & Ling, Liang-Han. (2021). A prospective STudy using invAsive haemodynamic measurements foLLowing catheter ablation for AF and early HFpEF: STALL AF-HFpEF. European journal of heart failure. 23. 10.1002/ejhf.2122.

6. Kaye, David & Byrne, Melissa & Mariani, Justin & Nanayakkara, Shane & Burkhoff, Daniel. (2020). Identification of physiologic treatment targets with favourable haemodynamic consequences in heart failure with preserved ejection fraction. ESC Heart Failure. 7. 10.1002/ehf2.12908.

7. Mitra, Biswadev & Mitchell, Rob & Cloud, Geoffrey & Stub, Dion & Nguyen, Minh & Nanayakkara, Shane & Miller, Jean‐Philippe & O’Reilly, Gerard & Smit, Devilliers & Cameron, Peter. (2020). Presentations of stroke and acute myocardial infarction in the first 28 days following the introduction of State of Emergency restrictions for COVID-19. Emergency Medicine Australasia. 32. 10.1111/1742-6723.13621.

8. Stehli, Julia & Dagan, Misha & Zaman, Sarah & Koh, Ji & Quine, Ed & Gouskova, Natalia & Crawford, Claudia & Dong, Michael & Nanayakkara, Shane & Htun, Nay & Stub, Dion & Dick, Ronald & Walton, Antony & Duffy, Stephen. (2020). Impact of Sex on Transcatheter Aortic Valve Implantation Outcomes. The American Journal of Cardiology. 133. 10.1016/j.amjcard.2020.07.052.

9. Nanayakkara, Shane & Byrne, Melissa & Mak, Vivian & Carter, Kaye & Dean, Eliza & Kaye, David. (2020). Extended‐Release Oral Milrinone for the Treatment of Heart Failure With Preserved Ejection Fraction. Journal of the American Heart Association. 9. 10.1161/JAHA.119.015026.

10. Gard, Emma & Nanayakkara, Shane & Kaye, David & Gibbs, Harry. (2020). Management of heart failure with preserved ejection fraction. Australian Prescriber. 43. 12-17. 10.18773/austprescr.2020.006.

11. Beale, Anna & Cosentino, Carmela & Segan, Louise & Mariani, Justin & Vizi, Donna & Evans, Shona & Nanayakkara, Shane & Kaye, David. (2020). The effect of parity on exercise physiology in women with heart failure with preserved ejection fraction. ESC Heart Failure. 7. 10.1002/ehf2.12557.

12. Gellatly, Rochelle & Connell, Cia & Tan, Christianne & Andrianopoulos, Nick & Ajani, Andrew & Clark, David & Nanayakkara, Shane & Sebastian, Martin & Brennan, Angela & Freeman, Melanie & O’Brien, Jessica & Selkrig, Laura & Reid, Christopher & Duffy, Stephen. (2019). Trends of Use and Outcomes Associated With Glycoprotein-IIb/IIIa Inhibitors in Patients With Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention. Annals of Pharmacotherapy. 54. 106002801988955. 10.1177/1060028019889550.

13. Ranasinghe, Mark & Ranasinghe, Marly & Nanayakkara, Shane. (2019). Evaluating a Multidisciplinary Diabetes Education Program for Improving Cardiovascular Risk and Glycaemic Control. 10.26226/morressier.5d9b622bea541d6ca8493a4d.

14. Sugumar, Hariharan & Nanayakkara, Shane & Chieng, David & Wong, Geoffrey & Parameswaran, Ramanathan & Anderson, Robert & Al-kaisey, Ahmed & Nalliah, Chrishan & Azzopardi, Sonia & Prabhu, Sandeep & Voskoboinik, Alex & Lee, Geoffrey & Mclellan, Alex & Ling, Liang-Han & Morton, Joseph & Kalman, Jonathan & Kistler, Peter. (2019). Arrhythmia recurrence is more common in females undergoing multiple catheter ablation procedures for persistent atrial fibrillation: Time to close the gender gap. Heart Rhythm. 17. 10.1016/j.hrthm.2019.12.013.

15. Nanayakkara, Shane & Telles, Fernando & Beale, Anna & Evans, Shona & Vizi, Donna & Marwick, Thomas & Kaye, David. (2019). Relationship of Degree of Systolic Dysfunction to Variations in Exercise Capacity and Hemodynamic Status in HFpEF. JACC: Cardiovascular Imaging. 13. 10.1016/j.jcmg.2019.09.016.

16. Sugumar, Hariharan & Nanayakkara, Shane & Chieng, David & Wong, Geoffrey & Parameswaran, Ramanathan & Anderson, Robert & Al-kaisey, Ahmed & Nalliah, Chrishan & Azzopardi, Sonia & Lee, Geoffrey & Mclellan, Alex & Ling, Liang-Han & Morton, Joseph & Kalman, Jonathan & Kistler, Peter. (2019). Gender specific long term multiprocedural outcome after catheter ablation for persistent Atrial fibrillation. Time to close the gender gap..

17. Cieslik, Luke & Patel, Hitesh & Steele, Simon & Beale, Anna & Tan, Christianne & Mariani, Justin & Nanayakkara, Shane & Kaye, David. (2019). Non-invasive blood pressure monitoring underestimates hypertensive response to exercise in suspected heart failure with preserved ejection fraction. European Journal of Preventive Cardiology. 27. 204748731987345. 10.1177/2047487319873452.

18. Kaye, David & Nanayakkara, Shane. (2019). Interatrial Shunt Device for Heart Failure With Preserved Ejection Fraction. 10.3389/fcvm.2019.00143.

19. Haregu, Tilahun N & Nanayakkara, Shane & Kingwell, Bronwyn & Jennings, Garry & Dart, Anthony & Carrington, Melinda & Kaye, David. (2019). The Baker Biobank: Understanding Cardiovascular Outcomes. Heart, Lung and Circulation. 29. 10.1016/j.hlc.2019.08.014.

20. Ranasinghe, Mark & Ranasinghe, Marly & Nanayakkara, Shane. (2019). Evaluating a Multidisciplinary Diabetes Education Program for Improving Cardiovascular Risk and Glycaemic Control.

21. Beale, Anna & Nanayakkara, Shane & Kaye, David. (2019). Impact of Sex on Ventricular-Vascular Stiffness and Long-Term Outcomes in Heart Failure With Preserved Ejection Fraction: TOPCAT Trial Substudy. Journal of the American Heart Association. 8. 10.1161/JAHA.119.012190.

22. Voskoboinik, Alex & Kalman, Jonathan & Nicholls, T. & Nanayakkara, Shane & Wong, Geoffrey & Prabhu, Sandeep & Nalliah, C. & Sugumar, Hariharan & Stub, D. & Kaye, David & Wong, Michael & Kotschet, E. & Taylor, Andrew & Kistler, Peter. (2019). Alcohol Abstinence in Moderate Drinkers with Atrial Fibrillation: Results from the Alcohol-AF Randomised Controlled Trial. Heart, Lung and Circulation. 28. 10.1016/j.hlc.2019.06.005.

23. Warren, Josephine & Nanayakkara, Shane & Andrianopoulos, Nick & Brennan, Angela & Dinh, Diem & Yudi, Matias & Clark, D.J. & Ajani, Andrew & Reid, Christopher & Selkrig, Laura & Shaw, James & Hiew, Chin & Freeman, Melanie & Kaye, David & Kingwell, Bronwyn & Dart, Anthony & Duffy, Stephen & Reid, C. & Ajani, Andrew & Investigators, Melbourne. (2019). Impact of Pre-Procedural Blood Pressure on Long-Term Outcomes Following Percutaneous Coronary Intervention. Journal of the American College of Cardiology. 73. 2846-2855. 10.1016/j.jacc.2019.03.493.

24. Meikle, Peter & Formosa, Melissa & Mellett, Natalie & Jayawardana, Kaushala & Giles, Corey & Bertovic, David & Jennings, Garry & Childs, Wayne & Reddy, Medini & Carey, Andrew & Baradi, Arul & Nanayakkara, Shane & Wilson, Andrew & Duffy, Stephen & Kingwell, Bronwyn. (2019). HDL Phospholipids, but Not Cholesterol Distinguish Acute Coronary Syndrome From Stable Coronary Artery Disease. Journal of the American Heart Association. 8. 10.1161/JAHA.118.011792.

25. Beale, Anna & Nanayakkara, Shane & Segan, Louise & Mariani, Justin & Maeder, Micha & Empel, Vanessa & Vizi, Donna & Evans, Shona & Lam, Carolyn & Kaye, David. (2019). Sex Differences in Heart Failure With Preserved Ejection Fraction Pathophysiology: A Detailed Invasive Hemodynamic and Echocardiographic Analysis. JACC: Heart Failure. 7. 239-249. 10.1016/j.jchf.2019.01.004.

26. Sugumar, Hariharan & Nanayakkara, Shane & Prabhu, Sandeep & Voskoboinik, Alex & Kaye, David & Ling, Liang-Han & Kistler, Peter. (2019). Pathophysiology of Atrial Fibrillation and Heart Failure. Cardiology Clinics. 37. 10.1016/j.ccl.2019.01.002.

27. Telles, Fernando & Nanayakkara, Shane & Evans, Shona & Patel, Hitesh & Mariani, Justin & Vizi, Donna & William, Jeremy & Marwick, Thomas & Kaye, David. (2019). Impaired left atrial strain predicts abnormal exercise haemodynamics in heart failure with preserved ejection fraction. European Journal of Heart Failure. 21. 10.1002/ejhf.1399.

28. Nanayakkara, Shane & Fogarty, Sam & Tremeer, Michael & Ross, Kelvin & Richards, Brent & Bergmeir, Christoph & Xu, Sheng & Stub, Dion & Smith, Karen & Tacey, Mark & Liew, Danny & Pilcher, David & Kaye, David. (2018). Characterising risk of in-hospital mortality following cardiac arrest using machine learning: A retrospective international registry study. PLOS Medicine. 15. e1002709. 10.1371/journal.pmed.1002709.

29. Nanayakkara, Shane & Kaye, David. (2018). Heart Failure With Preserved Ejection Fraction.

30. Patel, Hitesh & Yo, Shaun & Nanayakkara, Shane & Selkrig, Laura & Ellis, Matthew & Naughton, Matthew & Kaye, David & Mariani, Justin. (2018). The prognostic significance of chronotropic incompetence in patients with severe left ventricular systolic function referred for cardiac transplant assessment. European Journal of Preventive Cardiology. 27. 204748731878388. 10.1177/2047487318783880.

More research publications are available upon request. 

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