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Home • Specialist • Professor Michael O’Rourke

Biography

Professor Michael O’Rourke is a Cardiologist located at the St Vincents Hospital Sydney.

He has a special interest in hypertension, arterial haemodynamics, coronary artery disease, pre-hospital coronary care, community defibrillation, effects of aging on heart & arteries, and new methods for measuring arterial pressure.

He is a Fellow of the Royal Australasian College of Physicians, Royal College of Physicians in Ireland (Hon), Cardiac Society of Australia and New Zealand, European Society of Cardiology, American Heart Association, and American College of Cardiology.

Michael has greatly contributed to research and publications both internationally and nationally.

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Procedures & Conditions

Procedures Performed
  • General Cardiology
  • Arterial Haemodynamics
Conditions Treated
  • Hypertension
  • Coronary Artery Disease

Experience

  • Cardiologist
    St Vincent's Hospital Sydney Present
  • Emeritus Professor
    University of New South Wales

Memberships

Professional Memberships and Affiliations

  • Fellow of the Royal Australasian College of Physicians (FRACP)

  • Fellow of the Royal College of Physicians (FRCP) Ireland (Hon)

  • Fellow of the Cardiac Society of Australia and New Zealand (FCSANZ)

  • Fellow of the European Society of Cardiology (FESC)

  • Fellow of the American Heart Association (FAHA)

  • Fellow of the American College of Cardiology (FACC)

Research & Publications

Publications

1. O’Rourke MF; Takazawa K; Tanaka N, 2019, ‘Validity of noninvasive central aortic pressure measurement’, Journal of Hypertension, vol. 37, pp. 2300 – 2301

2. O’Rourke MF; Takazawa K; Tanaka N, 2019, ‘Letter by O’Rourke et al Regarding Article “Brachial and Radial Systolic Blood Pressure Are Not the Same: Evidence to Support the Popeye Phenomenon”‘, Hypertension (Dallas, Tex. : 1979), vol. 74, pp. e34

3. O’Rourke MF; Namasivayam M; Adji A, 2019, ‘Takotsubo cardiomyopathy: an extreme in the cardiovascular continuum?’, Journal of hypertension, vol. 37, pp. 501 – 503

4. Namasivayam M; McEniery CM; Wilkinson IB; Yasmin; Cockroft JR; McDonnell BJ; Adji A; O’Rourke MF, 2018, ‘Different effects of vascular aging on ischemic predisposition in healthy men and women’, Hypertension, vol. 72, pp. 1294 – 1300

5. Evensen KB; O’Rourke M; Prieur F; Holm S; Eide PK, 2018, ‘Non-invasive Estimation of the Intracranial Pressure Waveform from the Central Arterial Blood Pressure Waveform in Idiopathic Normal Pressure Hydrocephalus Patients’, Scientific Reports, vol. 8

6. Palatini P; Rosei EA; Avolio A; Bilo G; Casiglia E; Ghiadoni L; Giannattasio C; Grassi G; Jelakovich B; Julius S, 2018, ‘Isolated systolic hypertension in the young: A position paper endorsed by the European Society of Hypertension’, Journal of Hypertension, vol. 36, pp. 1222 – 1236

7. O’Rourke MF; Adji A, 2017, ‘Managing hypertension in children and adolescents’, Journal of Hypertension, vol. 35, pp. 417 

8. O’Rourke MF, 2017, ‘Calibration of SphygmoCor’, Journal of Hypertension, vol. 35, pp. 645

9. Adji A; O’Rourke MF, 2017, ‘Correspondence: Central aortic pressure calibration: “A bridge too far”?’, Journal of Hypertension, vol. 35, pp. 893 – 894

10. Kim MO; Li Y; Wei F; Wang J; O’Rourke MF; Adji A; Avolio AP, 2017, ‘Normal cerebral vascular pulsations in humans: Changes with age and implications for microvascular disease’, Journal of Hypertension, vol. 35, pp. 2245 – 2256

11. O’Rourke MF; Adji A, 2017, ‘Pressure Paradox: High Pulse Pressure and Low Mean Pressure Are Favorable Features in Young Adults’, Hypertension, vol. 70, pp. 493 – 495

12. Hashimoto J; O’Rourke MF, 2017, ‘Inflammation and arterial stiffness in chronic kidney disease: Cause or consequence?’, American Journal of Hypertension, vol. 30, pp. 350 – 352

13. Segers P; O’Rourke MF; Parker K; Westerhof N; Hughes A; Aguado-Sierra J; Aizawa K; Alastruey J; Allen J; Avolio A, 2017, ‘Towards a consensus on the understanding and analysis of the pulse waveform: Results from the 2016 Workshop on Arterial Hemodynamics: Past, present and future’, Artery Research, vol. 18, pp. 75 – 80

14. O’Rourke MF; Adji A; Nichols WW; Vlachopoulos C; Edelman ER, 2017, ‘Application of arterial hemodynamics to clinical practice: A testament to medical science in London’, Artery Research, vol. 18, pp. 81 – 86

15. Namasivayam M; McCready M; Adji A; O’Rourke MF, 2017, ‘The Role of Heart Rate in Diastolic Coronary Perfusion and Subclinical Myocardial Ischemia’, Journal of the American College of Cardiology, vol. 69, pp. 1647

16. O’Rourke MF; Adji A; Weber T, 2016, ‘Correspondence regarding: Distinct effects of losartan and atenolol on vascular stiffness in Marfan syndrome by Bhatt et al.’, Vascular Medicine (United Kingdom), vol. 21, pp. 70

17. Weber T; Eber B; Wassertheurer S; Hametner B; O’Rourke MF, 2016, ‘Nitrites/nitrates in heart failure with preserved ejection fraction’, Journal of the American College of Cardiology, vol. 67, pp. 1382 – 1383

18. Adji A; Kachenoura N; Bollache E; Avolio AP; O’Rourke MF; Mousseaux E, 2016, ‘Magnetic resonance and applanation tonometry for noninvasive determination of left ventricular load and ventricular vascular coupling in the time and frequency domain’, Journal of Hypertension, vol. 34, pp. 1099 – 1108

19. O’Rourke MF; Safar ME; Nichols WW, 2016, ‘To the Editor’, New England Journal of Medicine, vol. 374, pp. 1587 – 1588

20. O’Rourke MF; Safar ME; Nichols WW, 2016, ‘To the Editor’, New England Journal of Medicine, vol. 374, pp. 1587 – 1588

21. Kim MO; O’Rourke MF; Adji A; Avolio AP, 2016, ‘Central pulsatile pressure and flow relationship in the time and frequency domain to characterise hydraulic input to the brain and cerebral vascular impedance’, Acta Neurochirurgica, Supplementum, vol. 122, pp. 307 – 311

22. Kim MO; Adji A; O’Rourke MF; Avolio AP; Smielewski P; Pickard JD; Czosnyka M, 2016, ‘Change in pulsatile cerebral arterial pressure and flow waves as a therapeutic strategy?’, Acta Neurochirurgica, Supplementum, vol. 122, pp. 167 – 170

23. Kim MO; Eide PK; O’Rourke MF; Adji A; Avolio AP, 2016, ‘Intracranial pressure waveforms are more closely related to central aortic than radial pressure waveforms: Implications for pathophysiology and therapy’, Acta Neurochirurgica, Supplementum, vol. 122, pp. 61 – 64

24. O’Rourke MF; O’Brien C; Edelman ER, 2016, ‘Arterial stiffening in perspective: Advances in physical and physiological science over centuries’, American Journal of Hypertension, vol. 29, pp. 785 – 791

25. O’Rourke MF; Winter D, 2016, ‘Transfer function-derived central pressure and cardiovascular disease events: The Framingham Heart Study’, Journal of Hypertension, vol. 34, pp. 2487 – 2489

26. O’Rourke MF, 2016, ‘Carotid Artery Tonometry: Pros and Cons’, American Journal of Hypertension, vol. 29, pp. 296 – 298

27. Namasivayam M; Adji A; O’Rourke MF, 2016, ‘Evaluating the Hemodynamic Basis of Age-Related Central Blood Pressure Change Using Aortic Flow Triangulation’, American Journal of Hypertension, vol. 29, pp. 178 – 184

28. Adji A; O’Rourke MF, 2016, ‘Blood Pressure Measurement: A New Frontier?’, Journal of Clinical Hypertension, vol. 18, pp. 279 – 280

29. Stone J; Johnstone DM; Mitrofanis J; O’Rourke M, 2015, ‘The mechanical cause of age-related dementia (Alzheimer’s Disease): The brain is destroyed by the pulse’, Journal of Alzheimer’s Disease, vol. 44, pp. 355 – 373

30. O’Rourke MF; Adji A; Namasivayam M, 2015, ‘Interpreting Blood Pressure in Younger Adults’, Journal of the American College of Cardiology, vol. 66, pp. 329 – 330

More publications available upon request. 

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Presentations

  • O’Rourke MF; Adji A; Safar ME, 2018, ‘Structure and function of systemic arteries: Reflections on the arterial pulse’, in American Journal of Hypertension, pp. 934 – 940

  • O’Rourke MF; Jiang XJ; Ji W; Li Y-S; Adji A; Dong H; Peng M; Liu L, 2016, ‘RE-EVALUATION OF NITRATE TOLERANCE: A STUDY OF CENTRAL AORTIC PULSE WAVEFORM ANALYSIS’, in JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, ELSEVIER SCIENCE INC, Chicago, IL, pp. 2026 – 2026, presented at 65th Annual Scientific Session and Expo of the American-College-of-Cardiology (ACC), Chicago, IL, 02 – 04 April 2016

  • Adji A; Weber T; O’Brien C; O’Rourke M; Avolio A, 2016, ‘GENERATION OF AORTIC FLOW VELOCITY FROM DERIVED AORTIC PRESSURE WAVEFORMS USING AGE-SPECIFIC AORTIC IMPEDANCE MODELLING’, in JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, pp. E209 – E209

  • Adji A; Weber T; O’Brien C; O’Rourke M; Avolio A, 2016, ‘DISPARATE EFFECT OF EARLY WAVE REFLECTION IN AORTIC PRESSURE AND AORTIC FLOW VELOCITY WAVEFORM’, in JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, pp. E209 – E210

  • Adji A; O’Rourke MF; Avolio A, 2014, ‘Tracking of Central and Upper Limb Systolic Pressure Over the Normal Human Lifespan’, in CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS

  • Namasivayam M; Adji A; O’Rourke M, 2014, ‘DELINEATING THE MECHANISMS OF AGE RELATED BLOOD PRESSURE CHANGE’, in JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, ELSEVIER SCIENCE INC, pp. A1447 – A1447

  • Adji A; Kim M; O’Rourke MF; Avolio AP; Eide PK, 2012, ‘RELATIONSHIP BETWEEN CENTRAL PULSATILE AORTIC AND INTRACRANIAL PRESSURE IN HUMANS’, in HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Perth, AUSTRALIA, pp. 502 – 502, presented at 33rd Annual Scientific Meeting of the High-Blood-Pressure-Research-Council-of-Australia (HBPRCA), Perth, AUSTRALIA, 06 – 09 December 2011

  • Giudici F; Qian Y; O’Rourke M; Avolio A, 2012, ‘Simulation of reduction of proximal aortic stiffness by an elastic wrap and effects on pulse pressure’, in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, pp. 657 – 660

  • Namasivayam M; McDonnell BJ; McEniery CM; O’Rourke MF, 2009, ‘Wave Reflection Remains Important to Age-Related Aortic Blood Pressure Elevation Across the Human Lifespan’, in JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, ELSEVIER SCIENCE INC, Orlando, FL, pp. A215 – A215, presented at 58th Annual Scientific Session of the American-College-of-Cardiology, Orlando, FL, 28 – 31 March 2009

  • Weber T; Adji A; O’Rourke M, 2008, ‘Determination of pulse wave velocity as a practical clinical measure of arterial stiffness’, in JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, Berlin, GERMANY, pp. S159 – S160, presented at 18th Scientific Meeting of the European-Society-of-Hypertension/22nd Scientific Meeting of the International-Society-of-Hypertension, Berlin, GERMANY, 14 – 19 June 2008

  • Weber T; Lengauer S; O Rourke MF; Rammer M; Porodko M; Eber B, 2008, ‘Pulse waveform characteristics predict cardiovascular outcome and all cause mortality in patients undergoing coronary angiography’, in Journal of Hypertension, Lippincott Williams & Wilkins, Berlin, Germany, pp. S7 – S8, presented at Scientific Meeting of the International-Society-of-Hypertension, Berlin, Germany, 14 – 19 June 2008

  • Hirata K; O Rourke MF; Momomura S, 2008, ‘Flow augmentation index as a major risk factor for silent lacunar infarction’, in Journal of Hypertension, Lippincott Williams & Wilkins, Berlin, Germany, pp. S395 – S395, presented at Scientific Meeting of the International-Society-of-Hypertension, Berlin, Germany, 14 – 19 June 2008

  • Hirata K; O Rourke MF; Momomura S, 2008, ‘Flow augmentation index: A major independent risk factor for silent lacunar infarction’, in Circulation, Lippincott Williams & Wilkins, Philadelphia, PA, USA, pp. E413 – E413, presented at Circulation, 01 January 2008

  • Hirata K; Vlachopoulos C; Adji A; O’Rourke MF, 2003, ‘Sildenafil (Viagrafi) improves arterial stiffness and reduces left ventricular load in patients with congestive heart failure’, in JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, ELSEVIER SCIENCE INC, CHICAGO, ILLINOIS, pp. 164A – 164A, presented at 52nd Annual Scientific Session of the American-College-of-Cardiology, CHICAGO, ILLINOIS, 30 March – 02 April 2003

  • Hirata K; Adji A; Vlachopoulos C; O’Rourke MF, 2003, ‘Sildenafil improves left ventricular systolic function in patients with congestive heart failure: The role of wave reflections’, in JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, ELSEVIER SCIENCE INC, CHICAGO, ILLINOIS, pp. 264A – 264A, presented at 52nd Annual Scientific Session of the American-College-of-Cardiology, CHICAGO, ILLINOIS, 30 March – 02 April 2003

  • Hirata K; Adji A; Vlachopoulos C; Hayward C; O’Rourke M, 2003, ‘Sildenafil (Viagra (R)) reduces arterial stiffness and left ventricular load in congestive heart failure patients’, in CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, BLACKWELL PUBLISHING ASIA, MELBOURNE, AUSTRALIA, pp. A65 – A65, presented at 24th Annual Scientific Meeting of High-Blood-Pressure-Research-Council-of-Australia-Inc, MELBOURNE, AUSTRALIA, 25 – 29 November 2002

  • Hirata K; Adji A; Vlachopoulos C; Hayward C; O’Rourke M, 2003, ‘Sildenafil (Viagra (R)) improves left ventricular systolic function and reduces wave reflection in patients with congestive heart failure’, in CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, BLACKWELL PUBLISHING ASIA, MELBOURNE, AUSTRALIA, pp. A64 – A65, presented at 24th Annual Scientific Meeting of High-Blood-Pressure-Research-Council-of-Australia-Inc, MELBOURNE, AUSTRALIA, 25 – 29 November 2002

  • Vlachopouloss C; Griffiths K; Skilton M; O’Rourke M; Celermajer D, 2003, ‘Effect of caffeine on arterial stiffness and endothelial function’, in JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, ELSEVIER SCIENCE INC, CHICAGO, ILLINOIS, pp. 271A – 271A, presented at 52nd Annual Scientific Session of the American-College-of-Cardiology, CHICAGO, ILLINOIS, 30 March – 02 April 2003

  • Walsh PW; Avolio AP; Iliopoulos J; Gillies R; Manganas C; Newman D; O Rourke MF; Walsh W, 2003, ‘Aortic Wrap Device for Decreasing Cardiac Load’, in Proceedings of the World Congress on Medical Physics and Biomedical Engineering, World Congress on Medical Physics and Biomedical Engineering 2003, Sydney, Convention and Exhibition Centre, Sydney, Australia, pp. 2982 – 2982, presented at World Congress on Medical Physics and Biomedical Engineering 2003, Sydney, Convention and Exhibition Centre, Sydney, Australia, 24 – 29 August 2003

  • Hirata K; Vlachopoulos C; Adji A; O’Rourke M, 2002, ‘Reproducibility of pulse wave analysis in a double-blinded study’, in JOURNAL OF HYPERTENSION, LIPPINCOTT WILLIAMS & WILKINS, PRAGUE, CZECH REPUBLIC, pp. S168 – S168, presented at 19th Meeting of the International-Society-for-Hypertension/12th European-Society-of-Hypertension Meeting, PRAGUE, CZECH REPUBLIC, 23 – 27 June 2002

  • Vlachopoulos C; Hirata K; Hicks M; O’Rourke M, 2001, ‘Unfavorable effect of caffeine on the elastic properties of the aorta: Insights into the mechanism of action’, in JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, ELSEVIER SCIENCE INC, pp. 255A – 255A

  • Pauca AL; O’Rourke MF; Kon ND, 2001, ‘Prospective evaluation of a method for estimating ascending aortic pressure from the radial artery pressure waveform’, in Hypertension, pp. 932 – 937

  • Uebaba K; Fenghao XU; Takebe M; Takayanagi H; Tamaki S; Shibata H; Ishiyama H; Amano K; Kasahara H; O’Rourke MF, 2001, ‘Usefulness of impedance cardiography and pulse study for the evaluation of the pharmacological action of the depressants’, in Japanese Journal of Clinical Pharmacology and Therapeutics

  • Vlachopoulos C; Hirata K; O’Rourke MF, 2001, ‘Pressure-altering agents affect central aortic pressures more than is apparent from upper limb measurements in hypertensive patients: The role of arterial wave reflections’, in Hypertension, pp. 1456 – 1460

  • Liu Z; Iliopoulos J; Gillies RM; O Rourke MF; Avolio AP; Walsh WR, 2001, ‘Cyclic preconditioning of sheep aorta’, in Engineering; Physical Science in Medicine (eds.), Annual conference of engineering and the physical sciences in medicine, Annual conference of engineering and the physical sciences in medicine, Fremantle, WA, pp. 123 – 123, presented at Annual conference of engineering and the physical sciences in medicine, Fremantle, WA, 30 September – 04 October 2001

  • Uebaba K; Xu FH; Shibata H; Ishiyama H; Amano K; Kasahara H; Sindone AP; O’Rourke MF; Keogh AM, 1999, ‘GTN induced change of radial pressure pulse contour in cardiomyopathic patients’, in Japanese Journal of Clinical Pharmacology and Therapeutics, pp. 141 – 142

  • Frohlich ED; Safar ME; Brunner H; Mancia G; London G; O’Rourke M, 1998, ‘Editorial commentary’, in Hypertension, pp. 155

  • O’Rourke M; Reinlib L, 1998, ‘Priorities in heart failure research [5]’, in Circulation, pp. 296

  • Uebaba K; Sindone A; Keogh AM; Macdonald PS; O Rourke MF; Ishiyama H; Amano K; Xu H; Kasahara H, 1998, ‘Estimation of cardiac function by non-invasive tonometric measurements of the radial pulse pressure contours in cardiomyopathic patients’, in Australian and New Zealand Journal of Medicine, Adis International Limited, Frenchs Forest, NSW, pp. 1:114 – 1:114, presented at Australian New Zealand Journal of Medicine 1998, 01 January 1998

  • O’Rourke M; Gallivan S, 1997, ‘Telemedicine: Evaluation or stagnation’, in Studies in Health Technology and Informatics, pp. 48 – 52

More presentations available upon request.

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