Biography

Dr Bruce Walker is a Senior Cardiologist at the St Vincent’s Private and Public Hospitals in Sydney. He has a special interest in cardiac investigations and echocardiography, and a particular expertise in arrhythmias and pacemakers.

Bruce is a Fellow of the Royal Australasian College of Physicians (FRACP). He contributes his knowledge and experience to domestic and international research publications and conference presentations.

CLAIM MY PRE-MADE PROFILE

Procedures & Conditions

Procedures Performed
  • General Cardiology
  • Pacemaker Implantation
  • Cardiac Monitoring
  • Catheter Ablation
  • Implantable Cardiac Defibrillators (ICDS)
Conditions Treated
  • Arrhythmias

Experience

  • Consultant Cardiologist
    St Vincent's Private and Public Hospital Present

Memberships

Professional Memberships and Affiliations
  • Fellow of the Royal Australasian College of Physicians (FRACP)

Research & Publications

Publications

1. Lee W; Tay A; Walker BD; Kuchar DL; Hayward CS; Spratt P; Subbiah RN, 2016, ‘Accelerated graft dysfunction in heart transplant patients with persistent atrioventricular conduction block’, Europace, vol. 18, pp. 1837 – 1841

2. Lee W; Tay A; Subbiah RN; Walker BD; Kuchar DL; Muthiah K; Macdonald PS; Keogh AM; Kotlyar E; Jabbour A, 2015, ‘Impact of Implantable Cardioverter Defibrillators on Survival of Patients with Centrifugal Left Ventricular Assist Devices’, PACE – Pacing and Clinical Electrophysiology, vol. 38, pp. 925 – 933

3. Kuang XT; Li X; Anmole G; Mwimanzi P; Shahid A; Le AQ; Chong L; Qian H; Miura T; Markle T, 2014, ‘Impaired Nef function is associated with early control of HIV-1 viremia’, Journal of Virology, vol. 88, pp. 10200 – 10213

4. Wang LW; Walker BD; Omari A; Tay AE; Subbiah RN, 2014, ‘Metastatic Merkel cell carcinoma of the heart’, European Heart Journal, vol. 35, pp. 2927

5. Cheruvu C; Walker B; Kuchar D; Subbiah RN, 2014, ‘Successful ablation of incessant AV reentrant tachycardia in a patient on extracorporeal membrane oxygenation’, Heart Lung and Circulation, vol. 23

6. Nayyar D; Feneley M; Macdonald P; Keogh A; Kotlyar E; Walker B; Hayward C, 2013, ‘Non-invasive Determination of the Preload Recruitable Stroke Work Relationship in Patients with Heart Failure’, Heart, Lung and Circulation, vol. 22, pp. S84

7. Lee W; Tay A; Subbiah R; Walker B; Kuchar D; Muthiah K; Robson D; Hodkinson E; Macdonald P; Keogh A, 2013, ‘Impact of Implantable Cardioverter Defibrillators on Survival of Patients with Centrifugal Left Ventricular Assist Devices’, Heart, Lung and Circulation, vol. 22, pp. S79

8. Spina R; Granger E; Walker B; Subbiah RN, 2013, ‘Ventricular tachycardia in hypertrophic cardiomyopathy with apical aneurysm successfully treated with left ventricular aneurysmectomy and cryoablation’, European Heart Journal, vol. 34, pp. 3631

9. Cheruvu C; Huilgol R; Grabs A; Thorburn C; Kuchar D; Walker B; Subbiah R, 2013, ‘Refractory long QT syndrome and the role of left cardiac sympathetic denervation’, Internal Medicine Journal, vol. 43, pp. 458 – 461

10. Lee W; Kuchar DL; Walker BD; Subbiah RN, 2013, ‘Isolated ventricular noncompaction: Implications for mechanisms of sudden cardiac death’, PACE – Pacing and Clinical Electrophysiology, vol. 36

11. Brockman MA; Chopera DR; Olvera A; Brumme CJ; Sela J; Markle TJ; Martin E; Carlson JM; Le AQ; McGovern R, 2012, ‘Uncommon pathways of immune escape attenuate HIV-1 integrase replication capacity’, Journal of Virology, vol. 86, pp. 6913 – 6923

12. Matthews PC; Leslie AJ; Katzourakis A; Crawford H; Payne R; Prendergast A; Power K; Kelleher AD; Klenerman P; Carlson J, 2011, ‘HLA footprints on human immunodeficiency virus type 1 are associated with interclade polymorphisms and intraclade phylogenetic clustering’, Journal of Virology, vol. 85, pp. 4635

13. Foo D; Walker BD; Kuchar DL; Thorburn CW; Tay A; Hayward CS; MacDonald P; Keogh A; Kotlyar E; Spratt P, 2009, ‘Left ventricular mechanical assist devices and cardiac device interactions: An observational case series’, PACE – Pacing and Clinical Electrophysiology, vol. 32, pp. 879 – 887

14. Streeck H; Jolin JS; Qi Y; Yassine-Diab B; Johnson RC; Kwon DS; Addo MM; Brumme C; Routy JP; Little S, 2009, ‘Human immunodeficiency virus type 1-specific CD8+ T-cell responses during primary infection are major determinants of the viral set point and loss of CD4+ T cells’, Journal of Virology, vol. 83, pp. 7641 – 7648

15. Schneidewind A; Brumme ZL; Brumme CJ; Power KA; Reyor LL; O’Sullivan K; Gladden A; Hempel U; Kuntzen T; Wang YE, 2009, ‘Transmission and long-term stability of compensated CD8 escape mutations’, Journal of Virology, vol. 83, pp. 3993 – 3997

16. Brumme ZL; Brumme CJ; Carlson J; Streeck H; John M; Eichbaum Q; Block BL; Baker B; Kadie C; Markowitz M, 2008, ‘Marked epitope- and allele-specific differences in rates of mutation in human immunodeficiency type 1 (HIV-1) Gag, Pol, and Nef cytotoxic T-lymphocyte epitopes in acute/early HIV-1 infection’, Journal of Virology, vol. 82, pp. 9216 – 9227

17. Streeck H; Lichterfeld M; Alter G; Meier A; Teigen N; Yassine-Diab B; Sidhu HK; Little S; Kelleher A; Routy JP, 2007, ‘Recognition of a defined region within p24 GAG by CD8+ T cells during primary human immunodeficiency virus type 1 infection in individuals expressing protective HLA class I alleles’, Journal of Virology, vol. 81, pp. 7725 – 7731

18. Otway R; Vandenberg JI; Guo G; Varghese A; Castro ML; Liu J; Zhao JT; Bursill JA; Wyse KR; Crotty H, 2007, ‘Stretch-Sensitive KCNQ1 Mutation. A Link Between Genetic and Environmental Factors in the Pathogenesis of Atrial Fibrillation?’, Journal of the American College of Cardiology, vol. 49, pp. 578 – 586

19. Zaunders JJ; Munier ML; Kaufmann DE; Ip S; Grey P; Smith D; Ramacciotti T; Quan D; Finlayson R; Kaldor J, 2005, ‘Early proliferation of CCR5+ CD38++ antigen-specific CD4+ Th1 effector cells during primary HTV-1 infection’, Blood, vol. 106, pp. 1660 – 1667

20. Lichterfeld M; Yu XG; Waring MT; Mui SK; Johnston MN; Cohen D; Addo MM; Zaunders J; Alter G; Pae E, 2004, ‘HIV-1-specific cytotoxicity is preferentially mediated by a subset of CD8+ T cells producing both interferon-γ and tumor necrosis factor-α’, Blood, vol. 104, pp. 487 – 494

21. Sager PT; Veltri EP; Kuchar DL; Walker BD; Thorburn CW, 2003, ‘Ventricular tachycardia following ingestion of a commonly used antihistamine (multiple letters)’, Medical Journal of Australia, vol. 178, pp. 245 – 246

22. Kuchar DL; Walker BD; Thorburn CW, 2002, ‘Ventricular tachycardia following ingestion of a commonly used antihistamine’, Medical Journal of Australia, vol. 176, pp. 429 – 430

23. Allen TM; Kelleher AD; Zaunders J; Walker BD, 2002, ‘Supervised or structured treatment interruption (STI) and beyond…’, Biofutur, pp. 52 – 58

24. Tie H; Walker BD; Singleton CB; Bursill JA; Wyse KR; Campbell TJ; Valenzuela SM; Breit SN, 2001, ‘Clozapine and sudden death [10]’, Journal of Clinical Psychopharmacology, vol. 21, pp. 630 – 632

25. Vandenberg JI; Walker BD; Campbell TJ, 2001, ‘HERG K + channels: Friend and foe’, Trends in Pharmacological Sciences, vol. 22, pp. 240 – 246

26. Singleton CB; Walker BD; Campbell TJ, 2000, ‘N-3 polyunsaturated fatty acids and cardiac mortality’, Australian and New Zealand Journal of Medicine, vol. 30, pp. 246 – 251

27. Tie H; Walker BD; Singleton CB; Valenzuela SM; Bursill JA; Wyse KR; Breit SN; Campbell TJ, 2000, ‘Inhibition of HERG potassium channels by the antimalarial agent halofantrine’, British Journal of Pharmacology, vol. 130, pp. 1967 – 1975

28. Walker BD; Singleton CB; Tie H; Bursill JA; Wyse KR; Valenzuela SM; Breit SN; Campbell TJ, 2000, ‘Comparative effects of azimilide and ambasilide on the human ether-a-go- go-related gene (HERG) potassium channel’, Cardiovascular Research, vol. 48, pp. 44 – 58

29. Walker BD; Thorburn CW; Kuchar DL, 1999, ‘Recurrent atrial electrode displacement complicating a single lead VDD pacing system’, PACE – Pacing and Clinical Electrophysiology, vol. 22, pp. 1688 – 1691

30. Walker BD; Valenzuela SM; Singleton CB; Tie H; Bursill JA; Wyse KR; Qiu MR; Breit SN; Campbell TJ, 1999, ‘Inhibition of HERG channels stably expressed in a mammalian cell line by the antianginal agent perhexiline maleate’, British Journal of Pharmacology, vol. 127, pp. 243 – 251

More research publications available upon request.

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Presentations

  • Singleton CB; Walker BD; Bursill JA; Wyse KR; Valenzuela SM; Breit SN; Campbell TJ, 1999, ‘Potential cellular mechanism for the antifibrillatory properties of fish oils: Potent blockade of Kv4.3 current (I-to)’, in CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, pp. 279 – 279

  • Singleton CB; Walker BD; Tie H; Wyse KR; Bursill JA; Valenzuela SM; Qui MR; Breit SN; Campbell TJ, 1999, ‘Potential cellular mechanism for the antifibrillatory properties of fish oils: potent blockade of the Kv4.3 encoded transient outward current.’, in European Heart Journal, W B Saunders Company Ltd, Barcelona, Spain, pp. 575 – 575, presented at European Society of Cardiology, Barcelona, Spain, 01 – 01 August 1999

  • Walker BD; Singleton CB; Bursill JA; Wyse KR; Dwyer L; Qui MR; Valenzuela SM; Breit SN; Campbell TJ, 1999, ‘Perhexiline maleate inhibits the rapidly activating cardiac delayed rectifier potassium channel (IKr) in rabbit ventricular myocytes and the human ether-a-go-go-related gene (HERG) potassium current’, in Australian and New Zealand Journal of Medicine, Adis International Limited, Perth, WA, pp. 120 – 120, presented at Annual Scientific Meeting of Cardiac Soc. Aust. and N.Z, Perth, WA, 02 – 05 August 1998

  • Singleton CB; Walker BD; Campbell TJ, 1999, ‘Modulation of antiarrhythmic actions by myocardial ischaemia’, in Proceedings of the Australian Physiological and Pharmacological Society, 67th Meeting of Physiology and Pharmacology Society, University of Newcastle, NSW, pp. 125P – 125P, presented at 67th Meeting of Physiology and Pharmacology Society, University of Newcastle, NSW, 27 – 29 September 1999

  • Walker BD; Singleton CB; Bursill JA; Wyse KR; Dwyer L; Qui MR; Valenzuela SM; Breit SN; Campbell TJ, 1999, ‘Cisapride inhibits the human ether-a-go-go-related gene (HERG), potassium channel expressed in Chinese hamster ovary (CHO-K1) cells’, in Australian and New Zealand Journal of Medicine, Adis International Limited, Perth, WA, pp. 120 – 120, presented at Annual Scientific Meeting of Cardiac Soc. Aust. and N.Z, Perth, WA, 02 – 05 August 1998

  • Singleton CB; Walker BD; Bursill JA; Wyse KR; Dwyer L; Qui MR; Valenzuela SM; Breit SN; Campbell TJ, 1999, ‘Characterisation of the Kv4.3 encoded human transient outward current and its inhibition by an omega-3 fatty acid.’, in Australian and New Zealand Journal of Medicine, Adis International Limited, Perth, WA, pp. 153 – 153, presented at Annual Scientific Meeting of Cardiac Soc. Aust. and N.Z, Perth, WA, 02 – 05 August 1998

  • Tie H; Valenzuela SM; Walker BD; Singleton CB; Bursill JA; Wyse KR; Breit SN; Campbell TJ, 1999, ‘Blockade of the human ether-a-go-go-related gene (HERG) potassium channel by amitriptyline: Another mechanism for cardiotoxicity’, in European Heart Journal, W B Saunders Company Ltd, Barcelona, Spain, pp. 329 – 329, presented at European Society of Cardiology, Barcelona, Spain, 01 August 1999

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