Patients with severe aortic stenosis often develop symptoms that can restrict activities of daily living and the ability to care for themselves at home. These patients may benefit from replacement of their aortic valve, but only approximately 1 in 3 patients receive valve replacements each year.1
Patients may be asymptomatic for a prolonged period (known as a latent period) before the patient becomes symptomatic and presents with the symptoms of aortic stenosis. Once a patient exhibits symptoms of aortic stenosis, urgent treatment is required.
Patients with severe aortic stenosis have a survival rate as low as 50% at 2 years, and 20% at 5 years without aortic valve replacement. Without treatment, symptomatic aortic stenosis will eventually lead to death.2
Without treatment survival rates in patients with severe aortic stenosis are as low as 50% at two years.